Tuesday, July 31, 2012

Aleppo rebels say they stand firm in "regime's grave"

ALEPPO, Syria (Reuters) - The Syrian military has stepped up its campaign to drive rebels out of Aleppo, where fighters said they were holding firm, vowing to turn the country's largest city into the "regime's grave".

Opposition activists denied a government declaration that its forces had recaptured the Salaheddine district, in southwest Aleppo, straddling the most obvious route for Syrian troop reinforcements coming from the south.

A Reuters reporter heard helicopters firing heavy machineguns over the eastern part of the city on Tuesday for the first time in several days.

Hospitals and makeshift clinics in rebel-held eastern neighborhoods were filling up with casualties from a week of fighting in the city, a commercial hub drawn into the 16-month-long revolt against President Bashar al-Assad.

"Some days we get around 30, 40 people, not including the bodies," said a young medic in one clinic. "A few days ago we got 30 injured and maybe 20 corpses, but half of those bodies were ripped to pieces. We can't figure out who they are."

The opposition Syrian Observatory for Human Rights said more than 100 people, 73 of them civilians, were killed in Syria on Monday. It said five rebel fighters died during clashes with Syrian forces in Salaheddine.

Outgunned rebel fighters, patrolling in flat-bed trucks flying green-white-and-black "independence" flags, said they were holding out in Salaheddine despite a battering by the army's heavy weapons and helicopter gunships.

A fighter jet flew overhead, a reminder of the overwhelming military advantage still enjoyed by government forces.

'BASHAR'S FORCES WILL BE BURIED'

"We always knew the regime's grave would be Aleppo," said Mohammed, a young fighter, fingering the bullets in his tattered brown ammunition vest.

"Damascus is the capital, but here we have a fourth of the country's population and the entire force of its economy. Bashar's forces will be buried here."

So far, however, the government's superiority on the ground means rebels have had little success in holding on to urban territory. The rebels made a major push into Damascus two weeks ago, but were driven out.

The Syrian government has said it has recaptured Salaheddine. Reuters journalists in Aleppo have not been able to reach the neighborhood to verify who holds it.

The army's assault on Salaheddine echoed its tactics in Damascus earlier this month when it used its overwhelming firepower to mop up rebel fighters district by district.

Assad's forces are determined not to let go of Aleppo, where defeat would be a serious strategic and psychological blow.

Military experts say the rebels are too lightly armed and poorly commanded to overcome the army, whose artillery pounds the city at will and whose gunships control the skies.

"Yesterday they were shelling the area at a rate of two shells a minute. We couldn't move at all," a man calling himself a spokesman for the "Aleppo Revolution" said on Monday. "It's not true at all that the regime's forces are in Salaheddine."

Warfare has stilled the usual commercial bustle in this city of 2.5 million. Vegetable markets are open but few people are buying. Instead, crowds of sweating men and women wait nearly three hours to buy limited amounts of heavily subsidized bread.

In a city where loyalties have been divided, with sections of the population in favor of the Assad government, some seemed wary of speaking out in the presence of the fighters, many of whom have been drafted in from surrounding areas.

Asked about his allegiances, one man waiting at a police station that had been badly damaged by shellfire said: "We are not with anyone. We are on the side of truth."

Asked whose side that was, he replied: "Only God."

Others stopped members of the Free Syrian Army (FSA) and asked them to do something about the supply of bread and petrol.

Rebel fighters remain in control of swaths of the city, moving around those areas armed with assault rifles and dressed in items of camouflage clothing in an edgy show of confidence.

They were emboldened to strike at Aleppo and central Damascus by a July 18 explosion that killed four of Assad's top security officials.

BIG POWERS DIVIDED

With big powers divided, the outside world has been unable to restrain Syria's slide into civil war.

The only international military presence is a small, unarmed U.N. observer mission. A convoy carrying the head of the mission was attacked on Sunday and only the vehicles' armor prevented injuries, U.N. Secretary-General Ban Ki-moon said on Monday.

He gave no further details of the attack. U.N. officials said on condition of anonymity that the convoy of five vehicles was hit by small arms fire in Talibisa, some 17 km (10 miles) from Homs, in what they said was an opposition-held area.

Moscow has supported Assad and has shown no sign of abandoning him, blaming the West and Arab countries for stoking the revolt by backing the opposition. Russian Deputy Foreign Minister Gennady Gatilov said on Twitter: "Situation is really critical in Aleppo. It is clear that biased media by all means try to do work for the opposition when the latter fails."

France said it would ask for an urgent meeting of the U.N. Security Council to try to break the diplomatic deadlock on Syria, but gave no indication that Russia and China would end their longstanding policy of blocking measures against Assad.

In London, Syria's most senior diplomat resigned because he could no longer represent a government that committed such "violent and oppressive acts" against its own people, the British Foreign Office said. Charge d'affaires Khaled al-Ayoubi joins a growing list of senior Syrian defectors.

Amid growing concern about security on its frontier, Turkey sent at least four convoys of troops, missile batteries and armored vehicles to the border with Syria.

There has been no indication that Turkish forces will cross the border, and the troop movements may just be precautionary in the face of the worsening violence in Syria.

(Additional reporting by Yara Bayoumy in Beirut; writing by Giles Elgood; editing by Peter Graff, Michael Roddy and Mohammad Zargham)

Source: http://news.yahoo.com/aleppo-rebels-stand-firm-regimes-grave-005526632.html

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Kelly Ripa Nearly Kisses Jeremy Renner In Karaoke Challenge (VIDEO)

?Live! with Kelly? host Kelly Ripa got a little excited around actor Jeremy Renner on Monday, and it was all over a heated karaoke challenge.

When Ripa asked him what his go-to karaoke song was, he shot back, "I don't know, why, do you want to battle?"

When guest co-host Chris Harrison commented that conversation was getting "contentious," Ripa picked up on a different vibe. "I feel like we could potentially kiss each other." Renner jokingly puckered up, and after the moment passed, he revealed that his preferred karaoke jams are songs by Journey or Queen.

Renner was on the show to promote "The Bourne Legacy," which hits theaters August 10.

TV Replay scours the vast television landscape to find the most interesting, amusing, and, on a good day, amazing moments, and delivers them right to your browser.

Related on HuffPost:

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Source: http://www.huffingtonpost.com/2012/07/30/kelly-ripa-jeremy-renner_n_1720383.html

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Romney: 'Look to Poland' on Freedom (WSJ)

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Senegal's Niasse elected parliament speaker

Former Senegalese prime minister Moustapha Niasse was on Monday elected president of the national assembly following legislative elections on July 1.

Niasse, a member of the presidential coalition, faced off against Oumar Sarr of the Senegalese Democratic Party (PDS) which was the ruling party until March elections.

"We must be the worthy representatives of the Senegalese people," Niasse told lawmakers after his election.

The 72-year-old is a veteran politician who has served every regime since independence.

He was a member of cabinet for the country's first president Leopold Sedar Senghor, notably as foreign minister, prime minister for both Abdou Diouf and his successor Abdoulaye Wade and has also played a role as mediator in various crises on the continent.

Niasse ran for presidential office in 2000, 2007 and 2012, without success.

He will lead an assembly dominated by the presidential coalition, of which his Alliance of Forces for Progress (AFP) is a member, with 119 of 150 seats.

Former president Wade, who was thrashed by President Macky Sall in a contentious election in March, suffered a further defeat in parliamentary polls as his PDS won only 12 seats. Smaller parties share the rest of the seats.

The new national assembly has 64 women, double its predecessor, thanks to a law on parity which was adopted in 2010.

Source: http://news.yahoo.com/senegals-niasse-elected-parliament-speaker-162309306.html

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Monday, July 30, 2012

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Potential Career Alternatives For Law School Grads ~ Career Online ...

With the nation struggling through the worst economic crisis since the Great Depression and unemployment at levels not seen in more than a generation, many Americans are finding themselves in a position where their skills, education and training are either no longer in demand within the marketplace, or if they are able to secure a job, are not sufficient to provide a solid, steady income. For that reason, many people, including professionals with advanced degrees, are looking to branch out into other areas where their work experience and educational background can be applied sometimes in unexpected ways or in unconventional settings.

The law has not been untouched by the same forces affecting the rest of the economy. Law firms are downsizing, associates are being let go or are working more for less, and solo practitioners are having trouble getting their practices off the ground. Although the juris doctor degree is still a prestigious title and the need for lawyers is still substantial, law schools are graduating more students than the market can bear. Moreover, many of the services offered by lawyers and attorneys can be obtained online, from professionals in non-legal fields (such as accountants), or through other means which do not require an individual to hire an actual lawyer. Although lawyers must attend law school for three to four years, pay tens of thousands of dollars in tuition, and pass the bar exam, law school graduates and practicing attorneys are facing great uncertainty.

However, there is a silver lining to the dark clouds hovering over the legal field. The training law students receive in law school and the experience lawyers obtain through their practice provide a unique set of skills that translate well in other fields. Here are a few areas that offer opportunities for creative thinkers, and ways law school graduates and lawyers can effectively contribute to them:


Journalism

- One of the most important skills a law student or lawyer must have is writing ? in fact, many law school professors and practicing attorneys argue it is the most important skill. The law school curriculum is built around reading and writing, but speaking extemporaneously, speaking comfortably in public, and ?thinking on your feet? are also important skills a good lawyer must master. Reading, writing, and speaking are also precisely the skills required of any good journalist. Many high-profile journalists, including Geraldo Rivera and Jeff Greenfield, are lawyers by training. Law students learn to communicate clearly and synthesize ideas, both of which are critical journalism skills.

Real Estate

- Property law and contracts are two of the foundational courses taught in every law school, and real estate transactions are generally either facilitated by a lawyer, or involve some legal work done by an attorney. Law schools teach students how to negotiate and structure financial transactions, analyze contract terms, and assess the risks involved ? all of which are very useful in the field of real estate investment. Some of the biggest real estate moguls and businesspeople, such as Sam Zell, who once owned the Chicago Tribune and Los Angeles Times, are law school graduates.

Entrepreneurship

- Some of the most successful companies and businesses in the United States were either founded or are currently led by lawyers. Although many foodies rely on the Zagat restaurant guides to help them find the best places to eat, most would probably be surprised to learn that the husband-and-wife team behind them ? Tim and Nina Zagat ? actually met at Yale Law School and practice corporate law. Lawyers and entrepreneurs must be able to think critically and come up with creative solutions to challenges.

These are a few of the areas in which the skills of a lawyer can come in handy ? and none of them involve the actual practice of law. With an open mind and a little determination, law school grads can weather the current slowdown in the legal job market and find good positions, competitive income, and intellectual satisfaction in a variety of fields.

Marcelo Dieguez is a practicing lawyer at Diefer Law Group and specializes in employment law and as a sexual harassment lawyer in Orange County and throughout California.

Source: http://www.careeronlineblog.com/2012/07/potential-career-alternatives-for-law.html

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Helpful suggestions about Get yourself ready for Business Interviews


By no means disregard the price of getting ready for your business interviews. Business interviews are in fact stuff that individuals don't get ready for, which is quite strange. Whenever you take into consideration an interview, it is a lot more than anyone individual point. They will discover around they are able to in regards to you and will also be judged in a combination way. Chances are you'll end up being fantastic in every methods till that individual starts chatting. The opportunity to communicate effectively is crucial for company and several jobs. Anyone who goes into an interview, as long as they have effectively well prepared, will most likely do very well.

Proper preparing begins with being prepared for any kind of achievable issue that you could be asked within a enterprise interview. Prepare yourself is absolutely important, particularly for work interviews within this increasingly competitive industry. For example, jot down all you can about how precisely and your reason for the best particular person for the position. If you have experience, next jot down the way your experience will benefit your own prospective boss. Whatever the placement will be, take the work outline, and attempt to present yourself in a way that enables you to seem like the best particular person for the position. By doing this, you'll be able to answer any queries which come your own path.

By filling out your job application correctly, your prospective employers will look at you inside a diverse gentle. You should take into consideration the way a badly filled-out application will look, or maybe it's got espresso staining on it or even whatever. You should not have any difficulties with your job application. The correct answer is an easy task to fill in as well as look after. Examine your job application as you are completing it to ensure that you're such as every one of the information is asking for. Then compose using an proper pen unless they will require something specific. You should have someone a person believe in complete it rather.

Could that when you are brand new and to get something choosing your web business, it is challenging to gain a totally total training about something such as scented candles because of a great deal accessible details. We do understand that is surely an clear assertion to a lot of of you, that is not the case with every person. A single answer to this perpetual difficulty continues to be marketing community forums since become familiar with folks that are performing the same points while you. Don't assume all promoting techniques are compatible with all companies, and thus our own quick intros about any one certain method will help you use a far better feeling about how applicable it is. A great deal of what are the results within internet business may be the consequence of somebody deciding to test something out also it results in something new. With regards to making his full attention, you want to do this kind of however, not enough where this due to the fact difficult. In the event that folks are looking into one another's face for just about any period of time, it'll start to feel strange. To create the very best impression, you should eye contact is key a large amount of that time period however, not every second. You'll find nothing strange relating to this, as it is the way you typically maintain his full attention when conversing to individuals we satisfy.

You have to play this simply by ear canal, so to speak, and also pay out particular focus on what you perform when you're questioned a question. Individuals participate in normal vision movement when they are considering or perhaps wanting to remember. You would like to make adequate his full attention to exhibit you are honest however, not a great deal it gets not comfortable.

Each business interview features a good deal to instruct a person, whether the result can be positive or otherwise. Carry out some mindful investigation about every person that selection interviews a person. Any information regarding the individual's background character can be quite useful. Your goal should be to arrive on the interview along with the maximum amount of foreknowledge as possible.



Source: http://computersa-z.blogspot.com/2012/07/helpful-suggestions-about-get-yourself.html

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Sunday, July 29, 2012

DailyStarLeb: Iran leader: Stop exporting oil, make new economy http://t.co/e5iEvqTh

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Source: http://twitter.com/DailyStarLeb/statuses/229672398495051776

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Integra Pest Champions Intelligent Approach to Spider Control in ...

Integra Termite & Pest Control, the exterminator Dallas residents trust for all their pest management needs, is promoting their intelligent approach to pest control in Dallas, Fort Worth, and the surrounding communities.

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More Details about http://www.integrapest.net here.

Tweet This Dallas, Texas (July 3, 2012) -- Integra Termite & Pest Control, the exterminator Dallas residents trust for all their pest management needs, is promoting their intelligent approach to pest control in Dallas, Fort Worth, and the surrounding communities.

As the leading exterminator dallas, Integra Termite & Pest Control believes that effective pest control does not consist of up-to-date technology and methods alone, but also involves an in-depth understanding of the habits and biology of the species concerned.

For instance, there are nearly 900 species of spiders in the state of Texas, but only two groups of spiders are considered poisonous to humans. Tarantulas, jumping spiders, and wolf spiders are commonly mistaken as deadly due to their startling physical attributes. They are large and rather formidable-looking, but their bite is usually less harmful than an ordinary bee sting.

Should homeowners see evidence of the presence of spiders in or around their property, Integra Termite & Pest Control recommends that they take some time to learn the key differences between harmless and dangerous spiders. This will give property owners a general idea of how to safely handle the situation.

In order to reduce the risk of harm to humans and to prevent needless concern, they also strongly advise that homeowners research basic tips for keeping spiders -- deadly and harmless alike -- out of their homes.

Integra Termite & Pest Control also extends their intelligent pest control approach to rodents, wasps, mosquitoes, and other common household headaches. Currently, they are offering a special on their mosquito misting systems -- $200 off of professional installation services. Inquiries may be directed to integrapest@yahoo.com.

For questions on pest control dallas, contact Integra Termite & Pest Control at 817-498-5816 or visit www.IntegraPest.net for more information.

About Integra Termite & Pest Control, LLC

For more than 19 years, Integra Termite & Pest Control has been providing the kind of pest control dallas and Fort Worth residents can depend on to keep pests away from their homes and businesses. The company employs only environmentally-friendly products to get rid of pests like termites, rodents, and spiders.

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For more details, please search ? exterminator dallas and pest control dallas ? in Google for related informations.

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More Details about http://www.integrapest.net here.

Integra Pest Champions Intelligent Approach to Spider Control in Dallas

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Saturday, July 28, 2012

Check Out Many Of These Great Sportfishing Recommendations ...

Sport fishing is definitely a great way to supply a family group or even to appreciate getting outside. It could be a way to learn about science and biology. Whatever your reason for sportfishing, the following will greatly improve your encounter therefore making you a better fisherman when you go fishing.

Upon having connected a species of fish and it also begins receiving closer to your fishing boat, fall your rod and reel. It should be at waistline level. If your fish swims below your motorboat, place the suggestion of your own rod in the water and adhere to the fish. Observe the species of fish when you can and hold back until it gets tired. When it is tired it can roll to its part.

Sea food are always going to be around regardless of the time of day it can be, but you can find a couple of times through the day that they are much more lively. Early each morning and in the middle of the evening hours are the best instances to trap fish since these are their finest feeding instances.

Decide which kind of species of fish you need to get, and complement your devices to this dimensions and type of fish. For example, your hook dimension must be able to accommodate the average size of your ?focus on? seafood, your lure needs to be the sort of lure that normally attracts this type of sea food, and wights and bobbers must be ideal for the actual size of the species of fish and also the level in which it typically swims.

Tidy up all your wreck while you are completed sportfishing. Tend not to depart wads of sportfishing collection laying around for creatures to acquire tangled in or swallow. Get all outdated hooks and dispose of any equipment that pauses and do not leave it if you keep. Obviously, generally get any rubbish while you are accomplished.

Speak with the residents. In case you are fishing in the new place, talk to the neighborhood anglers, in the hope that they will talk about information and facts along with you. Yet another excellent destination to get advice about where you can find by far the most species of fish reaches a lure and tackle go shopping ? make absolutely certain to acquire plenty of products prior to looking for recommendations!

When searching for sportfishing hooks, remember that the size of the catch receives smaller since the catch number gets larger sized. By way of example, hooks size 10 to 14 would be the littlest ones, and really should be employed to capture crappies, perch and sunfish. Hooks scaled 6 or 8 are somewhat larger sized, and are used for capturing catfish, bass sounds and walleyes.

As was explained before, angling is a great way to reduce stress. There are few issues a lot more comforting when compared to a calm day at the lake. Expertise is key to getting an excellent fisherman. By making the most of the info you study from this short article then using it, you can come to be great at fishing.

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Source: http://getarticles.web-how-to.com/check-out-many-of-these-great-sportfishing-recommendations-2/

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Our Devs Weigh In: We Also Want To Watch The Olympics Instead Of Work

nbc-logo1Editor's Note: Rob Saurini is a hard working developer at TechCrunch, except for today. Today, he just wants to watch the Olympics, like a true patriot. So I've been sitting here for the past couple of hours searching for a way to watch the Olympics Opening Ceremonies when I should probably be doing actual work.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/8xozjCat9-k/

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Magnitude 6.6 quake hits off Papua New Guinea coast: USGS

Comoros, Guinea-Bissau, Paraguay, Nepal, Rwanda, Solomon Islands and Syria ? if they do not either strengthen their laws or provide national reports that are required of them before October 1. Here are some of the more valuable species found in those countries that conservationists worry about:

Source: http://news.yahoo.com/magnitude-6-6-quake-hits-off-papua-guinea-202511230.html

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Is Obama losing his brand?

Top Line

After weeks of blistering attacks on Mitt Romney's record, the Obama campaign is shifting gears. This week the campaign?released two ads featuring President Obama speaking straight to camera with a mostly positive tone, the first of their kind this cycle.

After an initial month of positive advertising in May, Team Obama has spent nearly all of its ad dollars on hard hitting negative messages against Romney for June and July. The campaign thus far has been about destroying Romney's business record. The problem is its unclear that approach is getting them where they want to be heading into the fall. There is little evidence suggesting Romney has been disqualified as an alternative in voters' minds. And there are some hints the attacks may be hurting the essential and carefully cultivated Obama brand. Hence the shifting gears.

Early on, the Obama campaign made the decision that to win this campaign, they had to make this a referendum on Romney. And once you go negative, it's hard to go back.

But can the president strike a balance? Attack with one hand, and deliver positive messages on the other? Check out this week's Top Line for more.

Source: http://news.yahoo.com/blogs/power-players-abc-news/obama-losing-brand-110650160.html

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Is Bleeding Heart Bakery Going Out of Business?

Bleeding Heart Bakery

Bleeding Heart Bakery.

Chicago Eater:

Following the recent announcement that Bleeding Heart Bakery founders Michelle and Vinny Garcia were splitting from partners Greg Mohr and Scott Weiner at the West Town location (which re-opens tomorrow as West Town Bakery & Diner), now comes word that the Garcias may be shuttering their final two locations, one of which, in Lakeview, just opened two months ago.

A Craigslist ad went up announcing a major sale of what appears to be all or most of Bleeding Heart's baking equipment. The sale is said to be taking place this Saturday and Sunday from 9 a.m. to 5 p.m. behind the Lakeview spot at 1351 W. Belmont.

Read the whole story at Chicago Eater

Contribute to this Story:

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Source: http://www.huffingtonpost.com/2012/07/28/is-bleeding-heart-bakery-_n_1714098.html

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Hassle Free Property Management Srevices at Door step !!!! - City of ...

Date Listed 27-Jul-12
Address Etobicoke, ON M9W 6K1, Canada
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Metro King Realty Inc.?s Property Management Services are built on superior quality and excellence to guarantee profitability and proper maintenance of all your properties hassle free. Knowing you are in safe hands will give you the peace of mind you deserve.

Please contact us for FREE ESTIMATE and if you have any questions.

SERVICES OFFERED:

? Friendly, prompt service.
? Advertising, interviewing and thorough screening via application, credit check and reference checks of prospective Tenants
? Legal documentation-Lease agreements in compliance with the Residential Tenancy Act.
? High Professional customer service to both our landlords and tenants.
? Maximization of rental incomes with low risks.
? Prompt rental disbursements directly to your personal account.
? Monthly Financial statements.
? Comprehensive web advertisements for your suite.
? Representation of Landlords as authorized agents in court and distribution of legal notices.
? Regular inspections to properties to protect your investment.
? 24/7 emergency on call services.
? Flexible showing times to maximize the prompt placement of a tenancy.
? Working with and effectively overseeing qualified trades people.

PACKAGES OFFERED:

1-SILVER PACKAGE


In this Package following services are offered:

* Rental Assessment of the property
* Fully advertisement of rental property on Multiple real estate web sites including MLS, besthomecollection.com, metrokingrealty.com,craiglist.org, kijiji.ca,zoocasa.com and more!!!
* Screening, applications, credit check, reference checks and interviews.
* Proper Feed Back
* Preparation of Customized lease agreement as per Landlords requirement
* Collection of first and last month's rent on Landlord's behalf
* Distribution of signed lease agreement to Landlord and Tenant

Keep on file any information pertaining to the tenant's application

Once the move-in of the new tenant has been taken place, then the landlord assumes all responsibilities of rent collection and day to day management of the property. Any additional services required will be done on a "per fee basis".

Lease Fee: One Month's Rent per one year lease Agreement

2- GOLD PACKAGE

In this Package following Pre-Leasing and Post-Leasing services are offered:

Pre-Leasing


* Rental Assessment of the property Fully advertisement of rental property on Multiple real estate web sites including MLS, besthomecollection.com, metrokingrealty.com,craiglist.org, kijiji.ca,zoocasa.com and more!!!
* Screening, applications, credit check, reference checks and interviews.
* Proper Feed Back
* Preparation of Customized lease agreement as per Landlords requirement
* Collection of first and last month's rent on Landlord's behalf
* Distribution of signed lease agreement to Landlord and Tenant
* Keep on file any information pertaining to the tenant's application

Post Leasing
* Monthly rent collection and depositing to landlords account
* Monthly invoicing
* Field all tenant calls
* Reporting of any routine required maintenance and repairs (new home construction service follow-ups are the responsibility of the landlord)
* Regular Property visits
* Pre and Post Leasing property inspections
* Regular communication with the landlord reporting any updates & concerns
* Regular communication with tenants and take care of their concerns
* Serving of N4's and collection of NSF fees

Lease Fee: One Month's Rent per one year lease Agreement+ Management

Fee : 6% on monthly Rent

I look forward to hearing from you soon,

IFTIKHAR AHMAD
Broker of Record
Metro King Realty Inc.
www.metrokingrealty.com
416-671-3861(Direct) ~ 416-249-8282 (Office)

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The first half of the real estate tax income tax reduction drop growth ...

["finance and economics" (Blog,Micro-blogComprehensive report])According to the JINGWAH times reports,Ministry of Finance24 released the ?first half of 2012 revenue analysis?, in whichPersonal income taxIncome falls bigger, than last year the corresponding period growth fell 43.4Percentage points. At the same time, and real estate related tax revenue also fell sharply.Ministry of finance tax department introduction, 1-6 month deed tax, real estate tax year-on-year drop respectively 9.9% and 8.5%, compared with the same period last year the growth rate dropped 37.4 and 27.9 percentage points.1-6 monthly personal income tax falls compared to the same period 8%, than last year the corresponding period growth fell 43.4 percentage points, wherein the salary income tax and individual industrial and commercial household production income tax a larger decline, down 11.8% and 14.6% respectively compared to the same period.

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Source: http://www.zloan.info/34493.html

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HBT: Red Sox fielding inquiries about Beckett

In terms of vagueness and TransactionSpeak, this from Rob Bradford of WEEI may be the most trade deadline story I?ve seen in a while:

According to a major league source, while the Red Sox have fielded some exploratory inquiries on right-hander Josh Beckett, such calls to this point have been little more than exercises in kicking the tires.

This reminds me of a Firesign Theatre line. Like ?There was something fishy about the butler. I think he was a Pisces, probably working for scale.? It just kinda rolls, says nothing and ultimately makes me laugh.

Source: http://hardballtalk.nbcsports.com/2012/07/26/the-red-sox-are-fielding-inquiries-about-josh-beckett/related/

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Kitchen Addition 91342 ? UAC Contractors ? General Contractors

We?ll enable you to sort through the endless possibilities of layouts, styles, lighting, fixtures, accessories and a lot more ? transforming your kitchen area in to a masterpiece that you simply along with your household will cherish forever. A kitchen renovation is really a complex job that is hinged on many distinct variables, involving anything from workspace preparing and color scheme option to time and budget considerations.

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We will let you sort from the endless possibilities of layouts, styles, lighting, fixtures, accessories and even more ? transforming your kitchen into a masterpiece that you simply as well as your household will appreciate for years. A kitchen renovation is really a complex job that is certainly hinged on many distinct variables, involving anything from workspace preparing and color scheme choice to time and finances factors.

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Source: http://www.uac-contractors.org/Blog/2012/07/26/kitchen-addition-91342-14/

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Friday, July 27, 2012

Genome of a fruit besieged

The banana genome has been unpeeled. The genetic makeup of Musa acuminata, a fertile banana species that gave rise to the seedless Cavendish and other clonal varieties people eat today, sheds light on the plant?s evolutionary history and ripening process. This information may also help researchers boost the crop?s resistance to fungal and viral pathogens threatening its survival. M. acuminata has 36,542 protein-encoding genes and 235 genes that make small snippets of protein-regulating RNA, called microRNAs, an international team of researchers reports online July 11 in Nature. The team also found the genetic remains of a pathogen called the banana streak virus scattered on 10 of the banana?s 11 chromosomes. ?It?s probably a footprint of an attack that was successful, but the banana somehow overcame it,? says Thomas Givnish, a plant ecologist and evolutionary biologist at the University of Wisconsin?Madison.


Found in: Genes & Cells

Source: http://www.sciencenews.org/view/generic/id/342617/title/Genome_of_a_fruit_besieged

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Study Pinpoints a Genetic Cause of Most Lethal Brain ... - Cancer Kick

EMBARGOED UNTIL: 2PM (ET), THURSDAY, JULY 26, 2012

Newswise ? New York, NY (July 26, 2012) ? Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice. The findings were published today in the online edition of the journal Science.

?Our findings are doubly important,? said study leader Antonio Iavarone, MD, professor of pathology and neurology at CUMC, and a member of the Herbert Irving Comprehensive Cancer Center (HICCC) at NewYork-Presbyterian Hospital/Columbia University Medical Center. ?From a clinical perspective, we have identified a druggable target for a brain cancer with a particularly dismal outcome. From a basic research perspective, we have found the first example of a tumor-initiating mutation that directly affects how cells divide, causing chromosomal instability. This discovery has implications for the understanding of glioblastoma as well as others types of solid tumors.?

The fusion of these two genes was observed in just three percent of tumors studied, so any therapy based on this particular genetic aberration would apply to only a small subset of glioblastoma patients. ?It?s unlikely that we will find a gene fusion responsible for most glioblastomas. But we may be able to discover a number of other gene fusions, each accounting for a small percentage of tumors, and each with its own specific therapy,? said co-senior author Anna Lasorella, MD, associate professor of pathology and pediatrics at CUMC and a member of the Columbia Stem Cell Initiative and the HICCC.

?This is a very exciting advance in our understanding of cancer, and perhaps a first step toward a personalized, precision approach to the treatment of glioblastoma,? said Stephen G. Emerson, MD, PhD, director of the HICCC and the Clyde ?56 and Helen Wu Professorship in Immunology at the Columbia University College of Physicians and Surgeons.

Glioblastomas are tumors that arise from astrocytes, star-shaped cells that make up the brain?s supportive tissue. Since astrocytes reproduce quickly and are supported by a large network of blood vessels, glioblastomas are usually highly malignant. It is estimated that these tumors affect about 10,000 people in the United States each year. Glioblastoma is typically treated with surgery, followed by radiation and chemotherapy. However, the disease is invariably fatal, with a median survival of about 14 months after diagnosis, even with aggressive therapy. Glioblastomas took the lives of Senator Edward Kennedy in 2009 and New York Mets all-star catcher Gary Carter in 2012.

Several common single-gene alterations have been observed in glioblastoma. ?However, therapies targeting these alterations have not improved clinical outcomes, most likely because they have systematically failed to eradicate the proteins to which the tumor is ?addicted,?? said Dr. Iavarone.

Dr. Iavarone and his colleagues suspected that glioblastomas might be addicted to proteins produced by gene fusions. Such fusions have been implicated in other cancers, notably chronic myelogenous leukemia (CML). Novartis AG?s (NYSE: NVS) drug Gleevec (imatinib), which targets a fusion protein responsible for CML, has proved to be highly effective in arresting the disease.

In the current study, the CUMC researchers conducted genetic analyses of glioblastomas from nine patients, looking specifically for gene fusions. The most common fusion they observed involved the genes FGFR (fibroblast growth factor receptor) and TACC (transforming acidic coiled-coil).

Although each gene plays a specific role in the cell, sometimes errors in the DNA cause two ordinary genes to fuse into a single entity, with novel characteristics that can lead to a tumor,? said co-senior author Raul Rabadan, PhD, assistant professor in the department of Biomedical Informatics and the Center for Computational Biology and Bioinformatics, Columbia Initiative in Systems Biology.

?We developed a new method for analyzing the cell?s genomic material,? he said. ?First we looked at pieces of the glioblastoma genome from several samples, and then we extended the analysis to a large set of glioblastomas from the Cancer Genome Atlas project, sponsored by the National Cancer Institute.?

The researchers discovered that the protein produced by FGFR-TACC acts by disrupting the mitotic spindle, the cellular structure that guides mitosis (the division of a cell into two identical daughter cells). ?If this process happens incorrectly, you get uneven distribution of the chromosomes. This condition, which is known as aneuploidy, is thought to be the hallmark of tumorigenesis,? said Dr. Iavarone.

When FGFR-TACC was introduced into the brain cells of healthy mice, aggressive brain tumors developed in 90 percent of the animals, confirming that this gene fusion can lead to glioblastoma.

In another experiment, mice with this form of glioblastoma were given a drug that inhibits FGFR kinase, an enzyme essential for the protein produced by FGRF-TACC to do its work. The drug was found to prevent abnormal mitosis and double survival time, compared with a control group of mice that did not receive the drug.

Dr. Iavarone is currently establishing a cooperative study group, including CUMC and other brain tumor centers around the country, to conduct the trials of FGFR kinase inhibitors. Preliminary trials of these drugs (for treatment of other forms of cancer) have shown that they have a good safety profile, which should accelerate testing in patients with glioblastoma.

?This work is the result of an ongoing collaboration between a traditional and a computational lab. The synergy between the two approaches allows us to tackle complex biological problems in a high throughput fashion, providing a global view to the genome of glioblastoma,? said Dr. Rabadan.

Dr. Iavarone?s paper is titled, ?Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma.? The other contributors are Devendra Singh (CUMC), Joseph Minhow Chan (CUMC), Pietro Zoppoli CUMC), Francesco Niola (CUMC), Ryan Sullivan (CUMC), Angelica Castano (CUMC), Eric Minwei Liu (CUMC), Jonathan Reichel (CUMC and Weill Cornell Medical College, New York, NY), Paola Porrati (Fondazione I.R.C.C.S Istituto Neurologico C. Besta, Milan, Italy), Serena Pellegatta (Fondazione I.R.C.C.S Istituto Neurologico C. Besta), Kunlong Qiu (Bioinformatics Center, BGI, Shenzhen, China) Zhibo Gao (Bioinformatics Center, BGI), Michele Ceccarelli (Biogem, Ariano Irpino (AV) and Dipartimento di Scienze Biologiche ed Ambientali, Universit? del Sannio, Benevento, Italy), Riccardo Riccardi (Catholic University, Rome, Italy), Daniel J. Brat (Emory University School of Medicine, Atlanta, Ga.), Abhijit Guha (University of Toronto, Toronto, Canada), Ken Aldape (M.D. Anderson Cancer Center, Houston, Tex.), John G. Golfinos (NYU Langone Medical Center, New York, N.Y.), David Zagzag (NYU Langone Medical Center), Tom Mikkelsen (Henry Ford Health System, Detroit, Mich.), and Gaetano Finocchiaro (Fondazione I.R.C.C.S Istituto Neurologico C. Besta).

This research was supported by National Cancer Institute grants R01CA101644, R01CA131126, R01CA085628, R01CA127643, and U54 CA121852-05; National Library of Medicine grant 1R01LM010140-01; National Institute of Neurological Disorders and Stroke grant R01NS061776; Partnership for Cure grant 7-78947; and grants from the Chemotherapy Foundation, the Associazione Italiana per la Ricerca sul Cancro, and the Italian Ministry of Health. Additional support was provided by Giuseppe Bruno, Marianne Mebane, and Denise and David Chase.

Drs. Iavarone, Lasorella, and Rabadan and CUMC have filed a patent application related to the diagnostic and therapeutic use of FGFR-TACC gene fusions. Otherwise, the authors declare no financial or other conflicts of interest.

Columbia University Medical Center provides international leadership in basic, pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders and includes the dedicated work of many physicians, scientists, public health professionals, dentists, and nurses at the College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. Established in 1767, Columbia?s College of Physicians and Surgeons was the first institution in the country to grant the M.D. degree and is among the most selective medical schools in the country. Columbia University Medical Center is home to the largest medical research enterprise in New York City and State and one of the largest in the United States.

The Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center and NewYork-Presbyterian Hospital encompasses pre-clinical and clinical research, treatment, prevention and education efforts in cancer. The Cancer Center was initially funded by the NCI in 1972 and became a National Cancer Institute (NCI)?designated comprehensive cancer center in 1979. The designation recognizes the Center?s collaborative environment and expertise in harnessing translational research to bridge scientific discovery to clinical delivery, with the ultimate goal of successfully introducing novel diagnostic, therapeutic and preventive approaches to cancer. For more information, visit www.hiccc.columbia.edu.

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Article source: http://www.newswise.com/articles/view/591769/?sc=rsmn

Source: http://cancerkick.com/2012/07/26/study-pinpoints-a-genetic-cause-of-most-lethal-brain-tumor-may-lead-to-new-treatment/

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Building A Home Internet Business To Make An Income Online ...

Most folk who turn to the internet to better their financial status are unaware of what it takes to make an income online, so this article covers the steps to actually building a home internet business to the point of generating internet income. The internet offers anybody with a computer and internet connection the opportunity to start a home internet business with a click of the mouse, but building a home internet business is where the challenge, work and excitement begin.

Too many people get totally disillusioned when they have not made an income online after a few days or weeks of starting their home internet business, but that is purely because they do not appreciate the fact that it takes time and effort to build a business online. The building process of a home internet business never stops and if you can appreciate that you will need to be continually building, extending, maintaining or making alterations then you will be well on your way to making an income online. Building A Home Internet Business Your need to get your website in front of as many people as possible who are looking for what your business has to offer, so the whole building process is geared to attracting vast numbers of targeted visitors to your home internet business. This involves making the presence of your business felt on the internet and this is the process of building that we are going to discuss here. It is important that you have a means of building your list. Offering an email newsletter is a good example and with an auto-responder set up your visitors will be able to subscribe to your newsletter and so you start the list building process. This will enable you to also send your list members broadcast messages from time to time. Ensuring that your website is search engine friendly is another important factor to ensure that you achieve good rankings in the search results and you can optimize your website for your chosen keywords yourself. There are many ways to start making the presence of your business felt and it is advisable to use a variety of methods. Building back-links to your website is what is needed to give you better rankings in the search engines and a very effective method is writing and submitting articles to the article directories on a regular consistent basis, using the author resource box to anchor your keyword phrase to your website. Exchange links with other websites to build your link popularity and add your link to web directories. Constructively post in forums with a link to your website in your signature. These methods can be totally free if you have the time to write and submit. If you are short of time you can always hire a ghostwriter to write your articles and invest in an article submitter for submitting your articles. Pay per click advertising is another way to get almost instant targeted traffic to your website. You can also place adverts on the respected classifieds sites. Social bookmarking and blogging are also quick ways to spread the word. Extending A Home Internet Business As far as your actual website or blog is concerned it is important to continually add new content, not only to please the search engines but to add interest to your site as well. You can continually expand your website by adding new pages which target different keywords, thus attracting different visitors. Monitor your rankings in the search engines for your chosen keywords and keep an eye on your competition and make adjustments to your site where necessary. As the presence of your home internet business starts to be felt on the internet the volume of traffic to your website will steadily increase and if this is not happening you know that you need to do more of the above disciplines. Maintaining Your Website Be sure to regularly maintain your website by way of checking that all your links are working. Check your download time. Remove unnecessary links. Add more up-to-date features. Keep your website current. Making Alterations To Your Website There may come a time that you are receiving a lot of traffic to your website but you are still not making an income online. What now? This is when you need to take a serious look at your website. Are you offering what you promised in your adverts? Can your visitors easily find what they are looking for? Is your website easy to navigate? Is your website displaying offers or adverts from other websites that are distracting your customers? Do you have irritating flashing banners on your site? Are you asking your visitors to fill out too many forms or lengthy surveys? Do you have a call to action section? Are you giving your visitors too many options? Are you offering too much information or non-relevant content? Many forums have a section where you can submit your website for a review. A good idea would be to go back to the forums where you have been posting and submit your site for a review, explain the problems you are experiencing and request honest feedback to help you solve the problem. You could join an SEO forum as well and submit your site for a review from a more specialized point of view. Making An Income Online As you can see from the above, there are many factors involved in building a successful home internet business, but once you have reached the stage that your website is being viewed by a large number of people on a daily basis who are in the market for what your home internet business has to offer and your website is clear in its offerings, that is when you will start making an income online. About the Author: Cynthia Minnaar is the owner and webmaster of www.cyns-home-biz.com, the home internet business site for online home business opportunities, ideas to start an online home business, internet income training and ideas to make an online home business income. Get your own website setup free and start making money online. You may publish my article provided you include the resource box.

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Thursday, July 26, 2012

Most of us have a home in just about any wonderful | Nick Safi ...

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Source: http://nicksafisoftwareblog.comicspace.com/2012/07/26/most-of-us-have-a-home-in-just-about-any-wonderful/

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Enyo's Out of Beta - but Will Devs Give it Love?

HP brought Enyo -- the open source object-oriented JavaScript framework for webOS -- out of beta this week, six months after the ill-fated operating system was contributed to the open source community. Enyo 2.0 now has a community of developers, a broad set of cross-platform user interface widgets, and a layout library for building apps that work across all form factors.


Source: http://ectnews.com.feedsportal.com/c/34520/f/632000/s/21b439c9/l/0L0Stechnewsworld0N0Crsstory0C757280Bhtml/story01.htm

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There's No Such Thing as ?Good? Writing ? The Active Voice

I mean this very literally, and it?s something I tell my students all the time: there?s no such thing as ?good? writing. Sometimes they?ll nod and say something like, ?Yeah, it?s all subjective. Every person likes different stuff and interprets things differently.? But that?s not what I mean. Writing does have quality norms, and those norms matter. A lot. But norms are not the same as ?good? and ?bad? as essential labels.

Here?s what I mean. We all know what I?m talking about when I say ?writing,? but it?s actually not all that practical to think of writing as a single thing. In actuality, writing is contextual, situational ? it?s?writings, plural. Business writing is quite different from literary writing, which is quite different from a cell-phone text, which is quite different from journalism, which is quite different from scientific writing, which is quite different from ad copy. A piece of writing that?s labeled ?good? in one of these areas might be considered ?bad? if it gets uprooted and plopped down in another. This specificity explains why it can be so difficult to transition from one kind of writing to another: writers internalize the norms of the kind of writing they usually do and then bring those norms with them to new situations in which they may not work so well.

Sure, you may say, the big things may differ, but the same basic mechanical rules apply across the board.

That?s reasonably (though not entirely) true, but mechanics are not the most important stuff when it comes to writerly success: if the mechanics of a piece of writing are a mess, it?s not going to be readable, but a piece of writing can be mechanically clean and still suck. In short, reasonably solid mechanics are essential for a high-quality piece of writing, but they?re not what make a piece of writing high-quality. The more global features are what do that, and global features are highly contextual.

Why does all this matter? Pragmatically speaking, it matters when you try to write in a new discipline or genre. If you import norms from your old genre, you might get burned, so make sure you analyze your target genre and pick up any important differences. Also, it means new kinds of writing come with learning curves, so you shouldn?t feel bad if it takes a while to get into the swing of things. Philosophically speaking, it?s nice to recognize that talking about writing as ?good? and ?bad? (which we all do) is merely a shorthand for what you really mean: ?good? writing is writing that satisfies or exceeds the needs or expectations of the target audience within its genre or discipline, and ?bad? writing is writing that fails to do that.

So, what does it mean to be ?a really good writer?? In my book, a really good writer is someone who can identify and adjust to the norms ?and expectations of different kinds of writing. That means the essential characteristics of a ?really good writer? are perception and flexibility.

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Source: http://the-active-voice.com/2012/07/25/theres-no-such-thing-as-good-writing/

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